PE-22-28
Research Peptide | Lyophilized Powder | Batch Tested
For laboratory research use only. Not for human or animal consumption. Insulated shipping · Styrofoam box available.
Product Overview
PE-22-28 is a synthetic peptide derived from spadin, an endogenous fragment of the sortilin propeptide. It selectively blocks the TREK-1 potassium channel and is studied as a fast-acting antidepressant research candidate.
No published certificates yet.
SKU & packaging
Nominal sizes describe the product label; measured results are listed in each batch report. Published reports do not confirm the batch allocated to a future order.
Product & documentation questions
How do I read the size and pack quantity?
The per-vial size and number of vials per pack are listed separately in the table. The displayed price is for one pack. A blend’s stated size can describe combined ingredients; check its product label and report for individual components.
How do I find the matching COA?
Match the product, SKU and batch number with the published report. Open the batch page to read the actual results, original report and laboratory verification link. Ask support to confirm the allocated batch if it is not on your order.
Does a purity result mean every test passed?
No. Identity, purity, fill and endotoxin are separate measurements. Read each reported result and unit. An absent result is not a pass, and a less-than result is not zero.
Research Information
PE-22-28 is investigated for TREK-1 channel inhibition and the downstream effects on serotonergic signaling, neurogenesis and synaptic plasticity in animal and cell models of depression, where TREK-1 blockade is associated with rapid antidepressant-like responses. Supplied strictly for in-vitro and laboratory research use only — not for human or animal consumption.
Learn more
Read research overviews, COA verification guides, and reconstitution notes in our Knowledge Hub.